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DNA methylation landscapes Pacific Oyster Mortality Syndrome

DNA methylation landscapes before and after Pacific Oyster Mortality Syndrome are different within and between resistant and susceptible Magallana gigas

Des chercheurs de l'IHPE ont publié dans Science of Total Environment leurs résultats qui permettent de mieux comprendre les interactions entre l'huître et le POMS et de mettre en évidence des biomarqueurs épigénétiques pour la gestion des maladies et la santé des huîtres.

Pacific oysters are frequently affected by Pacific Oyster Mortality Syndrome (POMS), a polymicrobial disease influenced by environmental factors.

This study investigates the role of epigenetics, focusing on DNA methylation changes in resistant and susceptible oysters under basal and POMS-induced conditions. We identified differentially methylated regions (DMRs) in the gills and mantle, revealing distinct methylation patterns linked to immune response, metabolism, and transport. A set of 1998 epibiomarker candidates for resistance/susceptibility and 164 for POMS exposure was identified.

These findings enhance understanding of oyster-POMS interactions and highlight epigenetic biomarkers for disease management and oyster health

Voir aussi

DNA methylation landscapes before and after Pacific Oyster Mortality Syndrome are different within and between resistant and susceptible Magallana gigas
Valdivieso A, Morga B, Degremont L, Mege M, Courtay G, Dorant Y, Escoubas JM, Gawra J, de Lorgeril J, Mitta G, Cosseau C, Vidal-Dupiol J
Sci Total Environ . 2025 Jan 25:962:178385. doi: 10.1016/j.scitotenv.2025.178385. 
 

Date de modification : 02 avril 2025 | Date de création : 02 avril 2025 | Rédaction : Tulip Communication