Un bottleneck sélectif lors de l'entrée dans l'hôte entraîne l'évolution de nouveaux symbiotes de légumineuses

"This paper is a collaboration between 2 Tulip labs (LIPME and EDB). We analysed the evolutionary dynamics of bacterial populations during the experimental evolution of a plant pathogen into a legume symbiont. Using a combination of whole-population sequencing, bacterial genetics and mathematical modeling, we showed that the entry into the host plant is the major selective force acting on these bacterial populations.

We also identified many adaptive mutations, that will fuel future work aiming at understanding the molecular bases of adaptation in our system”